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The federal government would have to take multiple steps before anthrax vaccine trials with children could be ethically considered, according to a March 2013 report from the Presidential Commission for the Study of Bioethical Issues.
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Perhaps the best way research enterprises can thank the volunteers who participate in studies is by sending them the study's findings in clear, simple lay terms.
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As many as 10% may be non-responders
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Since the initial description of variant angina by Prinzmetal in the late 1950s and the later confirmation of coronary artery spasm as its cause, clinicians have sought a means of reliably testing for this entity.
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Frequent premature ventricular contractions (PVCs) may lead to a cardiomyopathy or worsen a pre-existing cardiomyopathy.
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The use of dabigatran in patients with mechanical heart valves compared with patients receiving warfarin was associated with increased rates of thromboembolic and bleeding complications, thus demonstrating no benefit and an excess risk.
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In a study of men in the Veterans Affairs health care system with low serum testosterone levels, the use of testosterone therapy was associated with an increased risk of mortality, myocardial infarction, or ischemic stroke.
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Historically, men with high-risk prostate cancer were believed to have low survival rates after definitive treatment with either surgery or radiation. However, long-term results of dose-escalated radiotherapy of doses ≥ 75.6 Gy, along with long-term androgen deprivation therapy (ADT), demonstrate 5-year survival rate of 92%, 5-year biochemical control rate of 82%, and symptomatic local failure rate of 0%. Death from prostate cancer was only 5.5% at 10 years in men treated with high-dose radiation therapy and ADT.